Patient preferences and quality of life implications of ravulizumab (every 8 weeks) and eculizumab (every 2 weeks) for the treatment of paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria and eculizumab.

The pathophysiology of paroxysmal nocturnal hemoglobinuria and treatment with eculizumab

Paroxysmal nocturnal hemoglobinuria is a rare disorder of hemopoietic stem cells. Affected individuals have a triad of clinical associations - intravascular hemolysis, an increased risk of thromboembolism, and bone marrow failure. Most of the symptoms experienced in this disease occur due to the absence of complement regulatory proteins on the surface of the red blood cells. Complement activati...

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

Comparative Efficacy of Every 2 Weeks versus Every 6 Weeks Injections of Fluphenazine Decanoate

Background: Maintenance treatment of schizophrenia reduces relapse rates of this disease. This treatment is carried out for long periods of time and occasionally for lifelong. Dose reduction strategies are designed to maintain the benefits of antipsychotic drug therapy, while reducing the side effects. The authors tested a new dose reduction approach by increasing the interval between administr...

Comparative effectiveness of fluphenazine decanoate injections every 2 weeks versus every 6 weeks.

OBJECTIVE Dose reduction strategies for the maintenance treatment of schizophrenia are designed to maintain the benefits of antipsychotic drug therapy while reducing risks. Previous strategies with decanoate preparations have been based on the use of lower doses per injection to achieve dose reduction; these strategies have achieved dose reduction but have resulted in some increase in symptoms....